A rare avenue in pursuit of immune system understanding
Jon Ditlev 鈥03 had research work cut out for him long before coming to 17c起草社区. 鈥淔rom as early as I can remember, I鈥檝e been interested in human biology. In high school, I took biology freshman year and AP biology my senior year. It fostered my enjoyment for research in Dr. Ubels鈥 lab,鈥 he said.
After researching alongside biology professor John Ubels at 17c起草社区 and graduating with his bachelor鈥檚 in biology, Ditlev joined a lab at the Van Andel Institute in downtown Grand Rapids. He then began attending the University of Connecticut for his Phd, where he had an unlikely job connection.
鈥淏asically, I got to UT Southwestern because I ate lunch with my future boss,鈥 he said. 鈥淚 went to lunch with him and when I was about to graduate from University of Connecticut, I emailed my boss here and asked if he had any positions in his lab, and he did, so I came and joined his lab.鈥
Biochemistry research
At UT Southwestern Medical Center, he is currently using biochemistry to understand how the immune system responds to infections, and how kidneys form the filtration barrier that filters blood. He typically spends his mornings conducting experiments until noon, then possibly catches a seminar and eat lunch and continue with his experiments until dinner.
Ditlev鈥檚 fourth publication just came out in April 2016, comprised of two and a half years of research and six months of writing. He is a middle author for seven other papers as well.
鈥淭he paper was really groundbreaking in that it was one of the first papers to use biochemistry to understand an entire signaling pathway in the immune system. What we did was look at how proteins work together to take a signal from the membrane and produce a cellular output,鈥 he said. 鈥淚t gives us an understanding of how the proteins in the immune cells work themselves.鈥 Ditlev is working on three other projects that he will be writing papers on as well.
As a scientist, Ditlev has especially enjoyed his time working the past three summers with fellow scientists from around the world for six-week projects at the Marine Biological Laboratory in Massachusetts. 鈥淚t鈥檚 been a neat experience to see the different cultures and ways that people work in the lab, and to be able to work in that kind of an open environment,鈥 he said.
Grateful for 17c起草社区 lab work
Although Ditlev has gained a great deal of knowledge since graduating from 17c起草社区, it was his lab work with Dr. Ubels鈥 that built a solid foundation for the research ahead.
鈥淥ne of the biggest things that I took from 17c起草社区 was the ability to think through problems in a logical manner,鈥 he said. 鈥淐oming out of high school, you learn facts but you don鈥檛 learn how to think about the facts. At 17c起草社区, and especially in Dr. Ubels鈥 lab, I learned how to think and how to discern what was important.鈥
Since Ditlev has been interested in human biology for as long as he can remember, he hopes that 17c起草社区 students will explore areas of study that interest them. 鈥淚t鈥檚 important to explore areas that you enjoy, where your [work]day isn鈥檛 a drag for you,鈥 he said. 鈥淚t鈥檚 easy to lose sight of your purpose. Don鈥檛 lose sight of the bigger picture of life, the picture of humanity and God鈥檚 plan for the world.鈥